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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

11月,财新-Markit制造业采购经理人指数(PMI)从10月的51%降至50.8%,接近区分扩张和收缩的50%大关。此前,路透社(Reuters)对经济学家进行调查得出的预测中值曾预计,制造业PMI将降至50.9%。
10. “Results” (Andrew Bujalski)

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

深化农村改革。
Whedon had always loved the seemingly separate ideas of sci-fi and westerns, and through The Killer Angels, he saw a way to combine them. "I wanted to play with that classic notion of the frontier," he said. "Not the people who made history, but the people history stepped on—the people for whom every act is the creation of civilization." And Whedon decided to set the frontier on a spaceship: a ship named Serenity.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

Yao has been at the center of a hostile takeover battle for China's largest real estate developer China Vanke Co Ltd (000002.SZ).

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

它被广泛误解为一部关于小说家大卫·福斯特·华莱士(David Foster Wallace)的传记电影,其实庞索特的这部影片是一部关于新闻的坏方法的喜剧,以及对文学名誉机制充满了解的辛酸讽刺。杰西·艾森伯格(Jesse Eisenberg)与杰森·西格尔(Jason Segel)使用“男人老友电影”(buddy movie)的传统方式,完美地呈现出一个新的子类:亦敌亦友电影。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Recently, a recruitment website issued the Investigation Report of Employability of 2016 Graduates. The report notes that starting salaries for 2016 graduates are 4765 Yuan, nearly 30% graduates to enter the Internet industry which provide the highest average salary.
持有40亿美元亚洲相关资产的美国投资机构Cohen & Steers的基金经理梁纬濂(William Leung)认同这一点。他主张,随着价格下跌,投机性投资将被驱逐出市场。他补充称,行业中另类投资热度上升的趋势应当意味着,即便基础资产的价值上涨得更慢,房地产投资信托的价格也会上升。“我们认为,这次调整的幅度将不会太大,”他说。
Thank you to Aicha Nezzar for sharing this gem on the Facebook Group- Global English Forum.
The current El , a naturally recurring phenomenon that warms the Pacific Ocean, was probably only responsible for about 10 per cent of 2015’s record-breaking temperatures, he added.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

12月工业利润下滑突显出中国工业面临的产能过剩和价格下跌的困扰,这加大了中国政府放松货币政策并扩大基础设施支出,以缓和经济放缓影响的压力。
3.贾君鹏,你妈妈喊你回家吃饭。
《老友记》里几乎都是白人演员,所以它在当时并不是一部以兼容并包著称的电视剧。剧中的主要角色没有一个是"非主流"。甚至乔伊还经常拿罗斯的第一个老婆是同性恋这事开玩笑,而且经常能在台词中看到性别歧视的只言片语。
在这部暑期大片上映40年后,约翰·威廉姆斯的经典原声大碟仍然叫人毛骨悚然。《大白鲨》利用我们对未知的深海的本能恐惧,展示了一个多次受到同一条食人鲨袭击的海滨小镇。近年来,环保人士强调,鲨鱼通常不主动伤人,平均每年只有8人葬身鲨口。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

这部20世纪70年代黑色幽默犯罪电影的主角,是诈骗高手欧文·罗森菲尔德和他的情妇西德尼·普鲁塞尔,他们被一名联邦调查局(FBI)干员抓获,然后被迫欺骗腐败的政治家。二人继续与干员、政治家目标以及自己的家人周旋,最终达成豁免协议,得以不受任何刑事指控就脱离苦海。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

tox毒,ic-有毒的

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

在岛上海边的总督大楼,数万名支持群众等待罗塞略在宣誓就职典礼后的到来,手握着伞挡住炽热阳光。
温莎王朝的非官方座右铭“永不抱怨,永不解释”到底可信不可信?

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: LED产业到底是真胖还是“虚胖”?
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

为回应这起事件,借贷宝12月1日在其新浪微博上发表了一份公告,强调用裸照作抵押贷款是用户之间的私人交易,该公司无法加以管理。
That is changing. One big 2013 move for benchmark Brent crude came in August, when international intervention in Syria seemed increasingly likely. But while the price of Brent, which is traded on London's IntercontinentalExchange, did rise by 5% on the threat of U.S.-led airstrikes, it didn't come close to the 2013 high.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

An American actress, author, fashion designer, dancer, producer, and singer Jennifer Lopez hold the second place in the list of 10 most beautiful women of 2015. Lopez's personal relationships have attracted worldwide media attention; she has been married three times. Beside entertainment world, J. Lo enjoyed a highly successful business career, consisting of various clothing lines, accessories, fragrances, a production company, television shows and a charitable foundation among other business interests.
一位新浪微博网友写道:“不敢相信这么多医生都在论文中造假。病人还能相信他们可以帮人治病吗?”

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

pilot
北京大学和北京外国语大学的2017届毕业生平均月薪分别为9042元和9020元,位居第二、三位。
He was under the impression people clicking on the adverts would earn him money. But instead he was charged every time someone clicked on the link.
2. 谷歌文档

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

城镇新增就业1100万人以上,城镇登记失业率4.5%以内;

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

1. Apple. Brand love: 57% / Rank: 32
Investors in emerging markets need no reminder of the importance for EM assets of the US Federal Reserve — or do they?

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

今年的排行榜包括90个管理学硕士项目,创历来最高纪录,多于2015年的80个。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

两人的正式获奖词说的是表彰其“稳定匹配理论和市场设计实践”。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

祝大家2015年好运。(财富中文网)
'In the meantime, the U.S. continues to grow its own domestic production both in oil and gas. I think, for us, it's less about where the actual price is going--it's more about how much more growth is left in North American oil sands, shale gas, shale oil,' as well as shale exploration elsewhere, he said.
我曾被一位CEO要求雇用一位有着乌黑长发的长腿美眉,虽然她的能力不强。还有一次,我被要求不要雇用有小孩的应聘者,因为公司已经雇用了太多为了看足球赛请假的员工。这种事经常发生。
Putin had positive things to say about the Russian economy, saying it has "passed the crisis -- at least, the peak of the crisis."

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

German Three:Mercedes-Benz begins to sag as new lower-priced Benz’s inevitably erode its once invincible “the best or nothing” status. At BMW, imminent arrival of a new 7-series cements its status as the preferred brand of Scarsdale, Shaker Heights, and Santa Monica. A new A3, starting at $30, 795, should nicely lift Audi’s sales beyond 2014’s 15% climb, and a new Q7 SUV should nicely lift profits.
EMBAGlobal is the only programme in the top 10 that saw a slight drop in the average salary of its alumni compared with last year (the other nine recorded strong increases).
就零工经济的命运来说,英国将是一个值得关注的关键国家。英国政府将对一份关于英国法律是否跟得上这一新趋势的独立评估做出回应。考虑到政府的脆弱性和耗时的英国退欧进程,现在似乎不太可能出台大胆的政策行动——无论是支持还是反对在线劳动力平台。
adj. 民主的,大众的,平等的
“…did a song and dance routine in hopes of getting the job.”

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

张国立将主持2014年春晚
complex

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

奖项:尽管大众的高尔夫GTI先拔头筹,但偏向自家人的2015年北美汽车大奖的评审员们还是对福特的野马和F-150皮卡不吝溢美之辞。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Its brand value has increased by 22 per cent to $19bn and it has climbed 20 places up the ranking to number 50.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 解读2015年松木家具行业发展趋势
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

“Yao represents the new wave of wealth creation by financial investments in China,” said Rupert Hoogewerf, who compiles the annual list.
1. How to make pancakes
单词foundation 联想记忆:
但是,贝克?麦坚时律所并购业务主席迈克尔?德佛朗哥(Michael DeFranco)对中国企业在发达经济体投资表示赞赏。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: “留改拆”并举加快推进旧改
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

迷你剧集/电影类最佳男配角:斯特林?K?布朗(Sterling K Brown),《美国罪案故事:公诉辛普森》(The People v. O. J. Simpson: American Crime Story)
Only two people know the Oscars winners list and supervise the counting procedures - PwC tax adviser Martha Ruiz and Brian Cullinan an accountant.
Alice Schwarzer
库克决定通过增加派息和回购股票扩大其现金返还计划,帮助缓和了与维权投资者的关系。目前它总共向股东返还现金940亿美元。最终,库克以足够的坚忍抵挡住挑战,迎来了iPhone又一波增长捷报,以及从乔纳森?艾夫爵士(Sir Jonathan Ive)的设计室诞生的新产品。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

直到最近,Weill Cornell Medical College的科学家们至少在老鼠和猴子身上实现了这一点。这种人造视网膜,它的芯片可以将画面转换为电子信号,而它的微型投影机可以将电子信号转化为投影光线。
ZnS#k]Z047gSW1juv]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

研究显示,美国已经取代印度成为反倾销和其他贸易保护案件的最大发起国,而中国及其钢铁行业正是美国的最大目标。
Meanwhile, the University of Bradford School of Management and the University of Edinburgh Business School each climb 16 places, to 42nd and 55th, respectively. Judge Business School at the University of Cambridge rises 15 places to 14th.
单词circulation 联想记忆:
勇士的横扫,实际上让那些试图挑战勇士的球队无力追赶勇士的脚步,致使联盟在季后赛收入上损失惨重。于是,总决赛便成了战胜勇士的最后的希望,也是最后的机会。总有些愚蠢的人通过不断告诉你不要低估了勒布朗·詹姆斯来让你重燃希望。我看了所有五场詹姆斯在的总决赛,我现在客观的告诉你:詹姆斯知道自己赢不了。“我能做什么?他们赢了73场比赛,我打败了他们,于是他们引进了凯文杜兰特。”在凯文杜兰特用自己的冷血投射杀死系列赛之前,骑士还设法在三场比赛中夺得了一场胜利。但最后,骑士队虽然避免了横扫的尴尬,但他们结束赛季的方式也只能用虎头蛇尾来形容。
Summly and Yahoo refused to comment on the deal’s terms.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

While oil prices may rebound in 2015, they almost certainly won't return to $100 a barrel any time soon, barring a geopolitical crisis in a major petroleum-producing region. So the gift will keep giving this year and further feed an accelerating U.S. recovery.
Domain name registrar GoDaddy, which is based in Scottsdale, Ariz., broke ground in May on its new Global Technology Center in Tempe. GoDaddy already employs 2, 600 people in the Greater Phoenix area and the new facility is expected to add 300 more. Other companies expanding in Arizona include Asurion, a leader in technology protection services. They opened a new technical support center in Phoenix and want to fill 500 jobs by the end of the year. Energy provider Direct Energy opened a new call center in Tempe this year and is looking to fill as many as 300 openings.
史赛克公司(Stryker)的创始人就是“翻身床”的发明者,借助这个设备,卧床的病人无需挪动身体就能改变在病床上的位置。顺其自然地,这家医疗设备制造商也向自家员工及其家属出借医疗床,分毫不收。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

两名美国人因研究医生与医院、学生与学校和人体器官与被移植者之间的有效匹配,昨天被授予诺贝尔经济学奖。
The aspiring actress is also hoping her online following will secure her an audition to appear on ABC show 'Once Upon A time' which is adding Elsa as a character next season.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 2017年LED产业的几种发展趋势预测
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

9.Use One Planner
但英国法庭可能会沉重打击优步叫车应用。2017年,总部位于加州的该公司未能让上诉法官相信,其两名伦敦司机是独立的合同工。2018年,这个判例案件将会打到上诉法院,而且还可能打到最高法院。如果优步败诉,被要求承担起雇主的责任,那将会产生深远的影响。
11. MailChimp

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

[.?ndi'nai?bl]
4. Am I eating healthy? The types of foods we eat can greatly affect how we feel both physically and emotionally. Eating too much junk food can lead to crankiness and a relatively low energy level, whereas eating healthy foods can lead to better moods and a more positive energy level.
贴一些小便条来激励自己。一个美好的办公环境,还需要一些能够让自己提神的小纸条。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Schools relied on a wide range of technologies to ensure lively interactive delivery of their programmes including virtual classrooms, live sessions and multimedia teaching materials. Alumni were asked to rate delivery as well as indicate how effective online exams were. Results were encouraging. Schools appear to be getting better at online delivery. Every aspect of online delivery was rated higher than it had been in previous years, showing a greater level of satisfaction.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

但对于北京来说,若能在特朗普让美国退出TPP后不到一年的时间里达成RCEP协议,将是一场巨大的胜利。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

奥巴马取得胜利,也以为着在接下来四年的发展道路:关于国家开支、税收、医疗健康、政府的角色,还有应对中国发展和伊朗核问题等的外交措施。
na;F(|GWK@bR)

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 家居行业9名企业家上胡润百富榜
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

[k?mpi'tin]
Newcomers: Among the 15 newcomers on this year’s list are South Korean President Park Guen-hye (No. 11); Lockheed Martin CEO Marillyn Hewson (No. 34); CEO Tory Burch (No. 69); Spanx founder Sara Blakely (No. 90) and Baidu CFO Jennifer Li (No. 98).
8.Please aid the Olympic authorities and organisers by demonstrating at all times that you are not a terrorist. Do not perspire, take off your shoes, smile in a weird way while texting someone, or point and shout: "Hey! Look at all those missiles on that roof over there!" In fact, if you're not using your hands for anything, it's probably best if you keep them in the air where everybody can see them.
3.数学家

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“Soft domestic demand and the decline in commodity prices continued to weigh on China’s import growth,” said Liu Li-gang, an economist at ANZ bank. “Looking ahead, China’s export sector will continue to face significant headwinds.”
但是,租金稳定政策的反对者怀疑,在共和党人把持州议会的情况下,2015年将不会是租户运动的分水岭。舍温·贝尔金(Sherwin Belkin)是一名代表业主利益的律师,他说:“业主们认为可以借此机会对租金管制政策做一些亟需的改变。”

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Hua Xu Yin
Klay Thompson added 19 points and Andrew Bogut scored 13 for the Warriors, off to the best start by an NBA team since Dallas won its first 14 games in 2002-03. Golden State needs three wins to equal the league record of 15-0, held by the 1948-49 Washington Capitols and 1993-94 Houston Rockets.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

在这部暂未定名的电影里面,两段交错的三角恋,偏执,背叛等元素与音乐场面相互映衬。参演此片的有克里斯蒂安·贝尔(ChristianBale)、凯特·布兰切特(Cate Blanchett)、迈克尔·法斯宾德(Michael Fassbender)、瑞恩·高斯林(RyanGosling)、鲁妮·玛拉(Rooney Mara)以及娜塔丽·波特曼(Natalie Portman.)。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The regulations also specifically stipulate the taxi services.
Coming of age: in the modern banlieues of Paris and in San Francisco in the 1970s. These movies dramatize the harrowing, thrilling passage to womanhood with unsparing honesty and infinite compassion.
“Our population and employment is at an all-time high and growing. That puts significant pressure on rents and prices,” said Mark Willis, the executive director of the New York University Furman Center for Real Estate and Urban Policy. “There is no reason now to think that these trends are likely to change.”
'For now she wears a dab of lipstick and nail varnish.'

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

史赛克:免费医疗床
Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

不论是在那首一目了然的《IDGAF》(《我才不在乎呢》)中对情人的不屑一顾,还是在那首狂热的《Lost in Your Light》(《迷失在你的光芒中》)与米格尔热烈的音乐相和,她以些许艾蕾莎·贝丝·摩儿那种深沉的态度和些许希雅那种令人受不了的夸张,强烈地表达着自己的情感,但她也是一位比这两人都要热情的歌手。
3.8 推进以保障和改善民生为重点的社会建设
"Sure, there are only whites in the stadium. It comes down to money," said Ana Beatriz Ferreira, a 27-year-old parking attendant in Rio de Janeiro, who is black. "Nobody I know could find affordable tickets."

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Growth in the key sectors driving China’s economy softened last month, according to official gauges tracking activity at manufacturing, services and construction businesses.
与2013-2014赛季的世界各大足球联赛相比,本届世界杯的场均进球确实更多。荷甲以场均进球3.2个高居欧洲各大联赛之首,德甲则以3.16个紧随其后。上个赛季,其他联赛的场均进球都没有超过2.8个。目前,美国职业足球大联盟的场均进球为2.89个。
节目17 小品《你摊上事儿了》,秦海璐 王茜华 孙涛 方清平

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

8、苹果发布会
《自杀小队》将于2016年8月5日上映。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Yet there are similarities between the demagogic elements of the Brexit campaign and the rise of Mr Trump.
According to a research report on 2016 graduates released by 51job.com, a leading job hunting platform in China, 52.11% of college graduates found employment or started their own business.
Alumni from Edhec have the 11th highest average salary, at $105,000, behind the alumni from Sloan at $143,600. They also enjoyed theseventh-highest salary increase, at 79 per cent.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

人事工作类
说点实在的

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

To tackle the problems, the report suggests that e-commerce laws should be developed as soon as possible. It also calls for the establishment of an online credit system to strengthen the discipline of the e-commerce industry.
Amazon, Starbucks and Facebook have seen their brand values shoot up in 2016 compared with 2015. Amazon’s 59 per cent rise in value to $99bn and seventh place ranking, is partly due to its ability to create demand and not just satisfy it, according to Elspeth Cheung, head of BrandZ valuation at Millward Brown. She says Amazon’s one-hour delivery service has put pressure on other retailers to speed up delivery times while the online retailer’s move into logistics poses a threat to courier services UPS, FedEx and DHL.
Usually sober-minded analysts, accustomed to the auto industry’s slow growth, seem to shed their inhibitions when it comes to Tesla. Rod Lache of Deutsche Bank has attached a $310 price target on the stock. Not to be out-done, Adam Jonas of Morgan Stanley established a $320 price target and calls Tesla it the “most important car company in the world”.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 北京下架违法违规房源信息92万条
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Lucy Kay 成为亚军,而正太组合 Bars and Melody 位列第三。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: “冰丝带”上午全部“跃出”地面
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

贝尼托.墨索里尼(Benito Mussolini)和阿道夫.希特勒(Adolf Hitler)就是煽动家变身独裁者的经典例子。
Employment is crucial to ensuring people’s well-being. We will focus our efforts on facilitating employment to see that through their hard work, people can create wealth and realize their full potential.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Unlike several items on this list, artificial pancreas aren't still in some early development stage. The device very much exists and got FDA approval for sale this past September.
在婴儿出生前治疗出生缺陷

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Benchmark oil prices dropped below $40 a barrel last week, the lowest level in six years, darkening investor sentiment towards commodity-linked companies and exporting countries including Brazil, Russia and South Africa.
Will Theresa May remain prime minister in 2018

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: “非主流”小卖场产品质量堪忧
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

他说,本周早些时候他和美国国务卿克里的会谈显示,美国准备朝“解决只有通过共同努力方能解决的问题”的方向发展。
我们曾经都经历过:老板们和经理们让我们的生活越来越糟糕,不能管理好一堆文件,不理整个团队的员工。我之前写过一篇文章“不明智老板的特点”,在那篇文章里,一位考虑周到的评论者列出了他对如何做一个明智的老板的一些点评。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Written instructions apparently issued by China’s tourism administration, shown to the FT by one Beijing travel agent, order agencies to cancel group tours to South Korea booked for after March 15 and add that companies not in compliance could be fined or have their licences revoked. The tourism administration was not immediately available for comment.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.
supply
新年来临,祝新年快乐,愿你时时刻刻幸福欢乐!
伦敦——在20世纪70年代,英国喜剧演员汤米·库珀(Tommy Cooper)讲过这样一个笑话:他在阁楼里发现一把小提琴和一幅画,让拍卖公司估价。拍卖公司说,好消息是它们分别出自斯特拉迪瓦里(Stradivarius)和伦勃朗(Rembrandt)之手。坏消息是那幅画是斯特拉迪瓦里画的,小提琴是伦勃朗做的。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Another exceptional new field is that of nanotechnology.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

答:这是我第一次去旧金山。非常美丽的城市。到那儿的第一天我们就去看了金门大桥。海湾的景色真是让人愉悦啊。我在日本每次看电影,这个城市和这个桥都要被毁一次。但我从不知道这个城市亲眼看的话居然有这么美。下次再来可能就没机会看这座桥了,所以我很高兴这次能看到。
We will continue to work to see that government functions are fully carried out in accordance with law.
2008年,中国政府增加了一个归类为精神疾病的条目:"网瘾症"。据大量官方媒体报道,中国的年轻人花太多时间泡在网吧里,不顾家人和工作玩网络游戏到凌晨,有时甚至不吃,不喝,不睡眠,严重危害了自己的健康。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

穆里埃塔属于一个叫“五皇后”的黑帮,他们是加州淘金热的高潮期间,臭名昭著的土匪。虽然穆里埃塔的犯罪行为可能没有任何政治色彩,他还是随着来到加州投机的美国定居者,成了墨西哥抵抗的象征。对他而言,这可不是什么好事,而是促使政府悬赏他的人头,导致他被杀和斩首。幸运的是,班德拉斯的角色没有遭到同样的命运。
在那之前,她曾出演过大受欢迎的情景剧,并且也因饰演的角色而小有名气。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

面试官走进了壁橱,而不是会议室。
New Year’s greetings and best wishes!致新年贺忱与最美好的祝福!

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

5. It's a dog's life for the British

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Who was buried here?
Throughout Downsizing, I kept asking myself what the point of all of this was, never engaged by its hodgepodge of themes. I wish the filmmakers had asked that question too.
n. 冰箱

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

豆瓣网友“Banchengyansha”称:“电视剧版的场景很精致,也很贴合原著。”
A cheery New Year hold lots of happiness for you!
获奖者:哈里王子殿下
自该学校的国际管理学硕士(International Master in Management)项目首次被纳入榜单以来,该学校的排名在过去两年上升31个位置。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

生于缅甸皇室的杨金秀于7月31日去世。她拒绝了与生俱来的权利,成了一个女扮男装的军阀和鸦片走私犯。
周二在上海举办的中国国际机器人产业发展高峰论坛称,2017年,工业机器人的销量和增速均创新高。在这些工业机器人当中,有37825台为国产制造,同比增长29.8%。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

STONINGTON, CONN.
也许经济增长率是否能达到3%的国内最大威胁是利率的突然调整,但是从各方面的预测来看鸽派的美联储在2015年不太可能会采用挑衅的利率策略。
Julia Hartz

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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The ministry said that it had no tolerance for cheating and had asked public security departments to conduct an investigation.
Fifteen Chinese nationals have been charged with developing a fraud scheme in which they paid imposters to take entrance exams, including the SAT, and gained acceptance to elite American colleges and universities, the US Department of Justice said on Thursday. Conspirators were paid up to $6,000 each time they used counterfeit Chinese passports to trick test administrators into thinking they were the person who would benefit from the test score, a federal grand jury charged.重点单词

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